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Abstract #3665

RAIDER: Rapid, anatomy-independent, deep learning-based chemical shift-encoded MRI

Timothy JP Bray1, Giulio V Minore1, Alan Bainbridge2, Margaret A Hall-Craggs1, and Hui Zhang1
1University College London, London, United Kingdom, 2University College London Hospital, London, United Kingdom

Synopsis

Keywords: Fat & Fat/Water Separation, Fat

Motivation: Despite recent advances, chemical shift-encoded MRI (CSE-MRI) remains a challenging problem and many algorithms are computationally expensive, leading to interest in deep learning-based methods. However, initial attempts have used convolutional neural networks (CNNs), which are limited by data requirements, poor generalisability across different anatomies (‘anatomy-dependence’) and training time.

Goal(s): To address these limitations, we propose a deep learning-based method known as RAIDER.

Approach: RAIDER uses two multilayer perceptrons (MLPs), each trained separately with simulated single-voxel data, to achieve ultrafast parameter estimation.

Results: RAIDER is several orders of magnitude faster than conventional fitting, with similar/better performance, and avoids the inherent limitations of CNN-based methods.

Impact: RAIDER delivers ‘ultrafast’ CSE-MRI processing whilst avoiding the data and training-time requirements and anatomy-dependence of CNN-based methods. It could simplify, accelerate and reduce the cost of CSE-MRI processing in both research and clinical practice.

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Keywords