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Abstract #3673

4D spectral-spatial pulse design for subject-specific fat saturation at 1.5 T

Christian Karl Eisen1,2, Nicolas Groß-Weege3, Jürgen Herrler3, Patrick Liebig3, Michael Uder1, Armin Michael Nagel1,4, David Grodzki1,3, and Shaihan Malik2
1Institute of Radiology, University Hospital Erlangen, Friedrich-Alexander-Universität Erlangen-Nürnberg (FAU), Erlangen, Germany, 2Biomedical Engineering Department, School of Biomedical Engineering and Imaging Sciences, Kings College London, London, United Kingdom, 3Magnetic Resonance, Siemens Healthineers AG, Erlangen, Germany, 4Division of Medical Physics in Radiology, German Cancer Research Center (DKFZ), Heidelberg, Germany

Synopsis

Keywords: Fat & Fat/Water Separation, Spinal Cord, Gradients, Head & Neck /ENT, Parallel Transmission & Multiband, Simulations, System Imperfections: Measurement & Correction

Motivation: Insufficient fat saturation compromises image quality in clinical examinations.

Goal(s): To improve the quality of spectral fat saturation resulting in less residual fat signal in the acquired image.

Approach: Individual 4D spectral-spatial pulses based on subject-specific field maps and a numerically found trajectory are designed within an online workflow. A universal RF solution is also calculated. Performance is compared to Gaussian and SLR pulses on ten cervical spine datasets and one in-vivo measurement.

Results: Simulations show significantly improved fat saturation with individual and universal spectral-spatial pulses, while average water excitation remains low only for individual pulses. The in‑vivo measurement supports the simulation results.

Impact: Customized and universal spectral-spatial fat saturation pulses outperform currently used spectral pre-saturation pulses enabling more definitive interpretation of fat‑suppressed MR images. Potential application to a variety of sequences is straightforward by replacing the pre-saturation pulse with our design.

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