Keywords: Electromagnetic Tissue Properties, Electromagnetic Tissue Properties, MR EPT, conductivity, liver, brain, age-related changes
Motivation: Age-related study of electrical conductivity may be useful for personalized SAR modelling.
Goal(s): To evaluate in-vivo conductivity changes in a preliminary study in adults (brain and liver), using MR Electrical Properties Tomography, at 3T.
Approach: We used a UTE sequence to obtain RF-weighted images suitable for conductivity reconstruction. Data from 10 subjects were analyzed: in the brain, white matter and grey matter values were quantified; in the liver, fat volume fraction was also obtained for comparison.
Results: In-vivo conductivities were close to literature values, except for white matter which was higher in vivo. A significant dependency with age was found in the liver.
Impact: Knowledge of electrical properties of tissues is required for SAR modelling. Currently, values from ex-vivo/animal studies are used. In-vivo measurements by MR-EPT could bring valuable insights, in particular age-related changes, if existing, could be considered for MRI safety studies.
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