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Abstract #3721

In-vivo Validation of a Workflow to Predict Heating Around a Deep Brain Stimulation contacts

Nur Izzati Huda Zulkarnain-Lemke1, Alireza Sadeghi-Tarakameh1, Dee M Koski1, Noam Harel1, and Yigitcan Eryaman1
1Center for Magnetic Resonance Research (CMRR), University of Minnesota, Minneapolis, MN, United States

Synopsis

Keywords: Safety, Safety

Motivation: To develop a reliable method to predict heating around deep brain stimulation implants as a safety assessment prior to scanning patients.

Goal(s): To investigate the accuracy of a heating prediction workflow in-vivo.

Approach: We surgically inserted a DBS electrode into swine brains and predicted the heating around DBS contacts, with and without perfusion. Our heating prediction workflow uses a new MR-based current measurement, proposed for this work, as well as quasi-static electromagnetic and thermal simulations to predict heating around the electrical contacts of DBS electrodes.

Results: The predicted temperature around electrical contacts agreed with the measurements (NRMSE ≤ 0.09).

Impact: Our workflow predicts heating around the electrical contacts in-vivo without complex modeling and simulations. The results demonstrate the reliability of the workflow to assess heating risk before scanning patients with DBS implants.

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