Keywords: Quantitative Imaging, Image Reconstruction, Cardiac, Myocardial, T1 mapping, Single-Shot Sequence, qMR, NLINV, Subspace
Motivation: Volumetric quantification of$$$~T_1~$$$is highly desirable but limited by long acquisition times especially for motion-affected organs, such as heart. Therefore, conventional cardiac$$$~T_1~$$$mapping techniques are limited to single slices and suffer from low spatial resolution.
Goal(s): Develop a technique for rapid$$$~T_1~$$$mapping of multiple slices at high spatial resolution.
Approach: A radial slice-interleaved SMS readout was developed for single-shot IR-FLASH acquisition. NLINV subspace reconstruction is further proposed to jointly estimate subspace coefficient maps and coil sensitivities for all slices.
Results: Accurate$$$~T_1~$$$maps were achieved in a phantom and brain experiment for 9 slices within 4$$$~$$$seconds. Six cardiac short-axis myocardial$$$~T_1~$$$maps were reconstructed with an in-plane resolution of $$$1.25~mm^2$$$.
Impact: Multi-slice $$$T_1$$$ mapping has been achieved with a slice-interleaved radial SMS IR-FLASH acquisition and subspace NLINV reconstruction. This development may facilitate high resolution whole-heart myocardial $$$T_1$$$ mapping within a short breathhold (4 seconds).
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