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Abstract #3830

Towards online 3D MR-STAT reconstructions

Oscar van der Heide1,2, Stijn Heldens3, Alessio Sclocco3, Hongyan Liu1,2, Miha Fuderer1,2, Cornelis A.T. van den Berg1,2, and Alessandro Sbrizzi1,2
1Computational Imaging Group for MR Diagnostics & Therapy, Center for Image Sciences, University Medical Center Utrecht, Utrecht, Netherlands, 2Department of Radiology, Division of Imaging and Oncology, University Medical Center Utrecht, Utrecht, Netherlands, 3Netherlands eScience Center, Amsterdam, Netherlands

Synopsis

Keywords: Quantitative Imaging, Quantitative Imaging

Motivation: MR-STAT is a transient-state qMRI technique that can deliver T1, T2 and proton density maps from a single short scan, even when Cartesian trajectories are used. The non-linear model-based MR-STAT reconstruction procedure is challenging and current state-of-the-art reconstructions take multiple hours for a 3D dataset.

Goal(s): In this work we aim to accelerate the MR-STAT reconstructions to make the technique more valuable for clinical practice.

Approach: A highly-optimized CUDA EPG simulator was developed and an optimization for signal computations for Cartesian trajectories has been discovered.

Results: High-resolution 3D knee and brain MR-STAT datasets can now be reconstructed in 12.5 and 25 minutes, respectively.

Impact: The tools are part of the COMPAS Toolkit that is available online. These tools are relevant to other researchers or educators that require high-performance Bloch/MRI simulations.

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Keywords