Meeting Banner
Abstract #3897

Investigation the relationship between cerebral small veins and microbleeds using 7T QSM in Alzheimer’s disease

Laya Ashouri1, Sema Yildiz2, Felisha Ma2, Bradley N Delman2, Priti Balchandani2, and Akbar Alipour2
1Urmia University of Medical Science, Urmia, Iran (Islamic Republic of), 2Icahn School of Medicine at Mount Sinai, New York, NY, United States

Synopsis

Keywords: Alzheimer's Disease, Alzheimer's Disease

Motivation: Cerebral microbleeds (CMBs) are small hypointense lesions often associated with cerebral small vessel diseases like cerebral amyloid angiopathy and Alzheimer's disease (AD).

Goal(s): Our aim is to evaluate the feasibility of using ultra-high resolution QSM at 7T MRI to find a link between small veins and CMBs in AD.

Approach: We used 7T QSM to established a connection between CMBs and the venous vasculature to evaluate venous contributions to AD conditions.

Results: Our data support the notion that CMBs might not exclusively derive from arteries, but that venous contribution could play an important, yet not much explored, role in CMBs in AD cohorts.

Impact: Our results provide evidence of a potential connection between CMBs and small veins, suggesting a potential role for veins in AD.

How to access this content:

For one year after publication, abstracts and videos are only open to registrants of this annual meeting. Registrants should use their existing login information. Non-registrant access can be purchased via the ISMRM E-Library.

After one year, current ISMRM & ISMRT members get free access to both the abstracts and videos. Non-members and non-registrants must purchase access via the ISMRM E-Library.

After two years, the meeting proceedings (abstracts) are opened to the public and require no login information. Videos remain behind password for access by members, registrants and E-Library customers.

Click here for more information on becoming a member.

Keywords