Keywords: Gradients, Diffusion/other diffusion imaging techniques
Motivation: Second-order motion-compensated spin-echo (MCSE) DT-CMR is limited by long echo-times (TE), resulting in T2-related signal-loss.
Goal(s): Use the ultrahigh gradient-strength of the Connectom scanner to reduce TE of second-order MCSE DT-CMR.
Approach: A second-order MCSE DT-CMR pulse-sequence was developed. Ultra-high (180mT/m) and a high gradient-strength (80mT/m) were compared in acquiring in-vivo DT-CMR data at two cardiac phases.
Results: The substantial reduction in TE enabled by ultra-high gradient-strength resulted in improvements in signal-to-noise ratio (SNR) in both cardiac phases. To our knowledge this is the first report comparing the performance of second-order MCSE DT-CMR at ultra-high gradient-strength (Connectom) to widely available high gradient-strengths.
Impact: Second-order MCSE DT-CMR acquired using ultra-high diffusion gradient strengths increases SNR in both cardiac phases, paving the way for future clinical translation of efficient multiphase DT-CMR.
How to access this content:
For one year after publication, abstracts and videos are only open to registrants of this annual meeting. Registrants should use their existing login information. Non-registrant access can be purchased via the ISMRM E-Library.
After one year, current ISMRM & ISMRT members get free access to both the abstracts and videos. Non-members and non-registrants must purchase access via the ISMRM E-Library.
After two years, the meeting proceedings (abstracts) are opened to the public and require no login information. Videos remain behind password for access by members, registrants and E-Library customers.
Keywords