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Abstract #3926

First experience of pTX RF pulse design at 11.T MRI for whole brain imaging in vivo

Vincent Gras1, Alexis Amadon1, Michel Luong2, Franck Mauconduit1, Aurélien Massire3, Caroline Le Ster1, Denis Le Bihan1, Michel Bottlaender4, Alexandre Vignaud1, and Nicolas Boulant1
1BAOBAB, NeuroSpin, University Paris-Saclay, CEA, CNRS, Gif-sur-Yvette, France, 2DACM/IRFU, University Paris-Saclay, CEA, Gif-sur-Yvette, France, 3Siemens Healthineers, Courbevoie, France, 4UNIACT, NeuroSpin, University Paris-Saclay, CEA, CNRS, Gif-sur-Yvette, France

Synopsis

Keywords: RF Pulse Design & Fields, High-Field MRI

Motivation: Following the commissioning of the Iseult CEA 11.7 T whole-body MRI system, first in vivo human brain images have been acquired at 11.7T.

Goal(s): Our aim is to demonstrate the feasibility of whole brain imaging using an 8TX/32RX home-built RF coil and to test subject-tailored pulses as well as calibration-pTX pulses.

Approach: Using 9 in-vivo B1 maps of the brain, we prepared and tested tailored kT-point pulses and universal GRAPE pulses to be used in non-selective 3D sequences.

Results: Our retrospective pulse performance analysis confirms the feasibility of whole brain imaging at 11.7T both using subject tailored and calibration free pTX.

Impact: . At 11.7T, the heterogeneity of the pseudo-CP mode, the transmit efficiency and the SAR level are such that dynamic pTX and extensive RF pulse optimizations are essential for whole brain imaging applications.

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Keywords