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Abstract #3983

Correlation of Amide Proton Transfer Magnetic Resonance Imaging with Prognostic Factors in Rectal Adenocarcinoma

Caixia Zhang1, Guanshun Wang1, Yongzhou Xu2, Yinrui Yang1, Lizhu Liu1, Yanli Li1, Ruimin You1, and Zhenhui Li1
1Department of Radiology, The Third Affiliated Hospital of Kunming Medical University, Yunnan Cancer Hospital, Yunnan Cancer Center, Kunming, China, 2Philips Healthcare, Guangzhou, China

Synopsis

Keywords: Cancer, CEST & MT, Rectal Adenocarcinoma, APT, prognosis

Motivation: Improving the accuracy of imaging to assess prognostic factors in rectal adenocarcinoma.

Goal(s): Recognizing early rectal adenocarcinoma, assisting clinicians to achieve precision treatment.

Approach: Prospective enrollment of rectal adenocarcinoma patients without neoadjuvant therapy undergoing radical surgery for rectal cancer. Using their preoperative imaging data, investigate the correlation between APTw imaging and prognostic factors in rectal adenocarcinoma.

Results: APTw SI value are linked to T-stage and the presence of perineural invasion in rectal adenocarcinoma.

Impact: This study's results hold promise for the non-invasive identification of nerve invasion in rectal adenocarcinoma, offering a foundation for clinicians to pursue precise treatment strategies.

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