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Abstract #4008

Measurement of pancreas graft temperature during cold preservation in MR scanner

Jan Weis1 and Olle Korsgren2
1Department of Medical Physics, Uppsala University Hospital, Uppsala, Sweden, 2Department of Immunology, Genetics and Pathology, Uppsala University, Uppsala, Sweden

Synopsis

Keywords: Pancreas, Thermometry, pancreas graft, MR spectroscopy, hypothermic storage, temperature

Motivation: Phosphorus (31P) and proton (1H) MRS are methods of choice in assessment of pancreas graft quality before transplantation. Since MR scanning can increase the temperature of the pancreas graft, measurement of the graft temperature is desirable.

Goal(s): The aim of this study was to investigate if it is possible to measure pancreas graft temperature in MR scanner using 1H-MRS.

Approach: Single-voxel 1H-MRS. Temperature constants were obtained by calibration experiments with the water-vegetable oil phantom.

Results: The present study has shown that 1H-MRS is able to measure the graft temperature during MR scanning.

Impact: 1H-MRS is able to measure the pancreas graft temperature during MR scanning. The temperature is computed from the chemical shift difference between water spectral line and methylene (CH2)n line originating from the pancreatic adipocytes.

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