Keywords: Dementia, Neuroscience, volumetry analysis, verbal fluency test
Motivation: To investigate whether there are correlations between regional brain volume and the categorical verbal fluency test (CFT).
Goal(s): While the relationship between CFT and the region of cerebral infarction or brain function has been investigated, it remains uncertain whether they also correlate with local brain volume.
Approach: We used a multiple regression analysis with age, gender, and total brain volume as covariates to examine the relationship between 267 community residents' cortical volume and CFT scores. A 3D high-resolution brain MRI captured the images.
Results: The volume of the left inferior frontal gyrus had a significant correlation with the CFT.
Impact: This result suggests a potential association between brain volume and various neuropsychological impairments. Furthermore, it motivates the exploration of a novel time-based examination of the manifestation of changes in brain metabolism, function, and volume in the context of neuropsychological alterations.
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