Keywords: RF Pulse Design & Fields, RF Pulse Design & Fields, Reduced FOV; 3D EPI;
Motivation: Universal pulses have been shown to be robust to B1+ inhomogeneity for brain imaging at 7T, without time-consuming online design. A similar approach may be useful for designing multidimensional RF pulses for the 3D prostate imaging at 3T.
Goal(s): To design a universal multidimensional refocusing pulse and demonstrate its potential use for reduced field-of-view imaging in the prostate.
Approach: A three-dimensional universal refocusing pulse was designed using 6 subjects and validated in 12 subjects and in vivo prostate imaging at 3T.
Results: The proposed 3D universal refocusing pulse achieved similar performance on seen and unseen subjects. We successfully acquired reduced field-of-view prostate images.
Impact: Our simulation and in vivo results demonstrated the potential to design one universal 3D refocusing pulses for most subjects in prostate imaging.
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