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Abstract #4144

Multi-shot DWI has a high sensitivity in hepatic NET metastasis detection, outperforming multiplanar T2w imaging

Surbhi Raichandani1 and Ryan Brunsing2
1Stanford University, Palo Alto, CA, United States, 2Radiology, Stanford University, Palo Alto, CA, United States

Synopsis

Keywords: Liver, Diffusion/other diffusion imaging techniques, oncologic imaging, rapid protocol, T2 weighted, neuroendocrine tumor, hepatic metastasis, multi-shot DWI, surveillance imaging, tumor assessment, Gadoxetate

Motivation: Liver metastasis detection without intravenous contrast has potential applications in MRI surveillance and whole-body imaging.

Goal(s): To compare multishot DWI (msDWI) and T2w imaging with fat suppression (T2w+FS) in detecting neuroendocrine tumor (NET) liver metastases.

Approach: We retrospectively determined the visibility of 114 lesions (35 patients) on msDWI and multiplanar T2w+FS. Sensitivities were calculated.

Results: msDWI outperforms T2w+FS, with sensitivity approaching 90% for lesions <=5mm.

Impact: HBP (Gadoxetate) imaging is the gold standard for detecting liver metastases, however rapid MRI without intravenous contrast is attractive from a cost and patient perspective. msDWI alone may prove sufficient for NET metastasis detection.

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Keywords