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Abstract #4145

A study based on MRI features to assess vessels that encapsulate tumor clusters and microvascular invasion in hepatocellular carcinoma

Zixin Liu1, Tao Zhang1, Xueqin Zhang1, and Xiance Zhao2
1Nantong Third People's Hospital, Nantong, China, 2Philips Healthcare, Shanghai, China

Synopsis

Keywords: Liver, Liver, HCC, VETC, MVI

Motivation: Vessels encapsulating tumor clusters (VETC) and microvascular invasion (MVI) are distinct vascular patterns of metastasis in hepatocellular carcinoma (HCC). Studies have indicated that patients with VETC+/MVI+ HCC have the worst long-term outcomes.

Goal(s): To establish a model based on MRI features of Liver Imaging Reporting and Data System (LI-RADS) v2018 for predicting VM (+) (VETC+/MVI+) HCC and assess its prognostic value.

Approach: Retrospective study.

Results: Size, arterial peritumoral enhancement, and peritumoral hypointensity on hepatobilary phase (HBP) are independent predictors of VM (+) HCC. The high-risk and low-risk groups predicted by the combined model show significant differences in recurrence-free survival (RFS) and early recurrence.

Impact: Preoperative non-invasive identification of VETC+/MVI+ HCC assists clinical physicians in formulating individualized treatment plans, thereby improving patient survival rates.

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