Keywords: Liver, Liver
Motivation: To explore the prognostic parameters related to microvascular invasion (MVI)-negative HCC patients.
Goal(s): The aim of this study was to establish a model for predicting the prognosis of patients with MVI-negative HCC based on qualitative and quantitative analyses of Gd-EOB-DTPA MRI.
Approach: Totally, 122 patients were retrospectively enrolled. Multivariate logistic regression analysis was performed to identify significant clinical parameters, and quantitative and qualitative MRI parameters associated with prognosis.
Results: Multivariate analysis showed that lower RER, HBP hypointensity without APHE, LI-RADS category, mild-moderate T2 hyperintensity, and higher AST levels were risk factors associated with prognosis. The most appropriate threshold value for RER was 1.197.
Impact: The nomogram incorporated preoperative qualitative and quantitative parameters and laboratory indices, namely LI-RADS category, HBP hypointensity without APHE, lower RER, mild-moderate T2 hyperintensity, and higher AST levels, can be a reliable tool for predicting prognosis in patients with MVI-negative HCC.
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