Keywords: Liver, Tissue Characterization
Motivation: To ensure successful integration of hepatic T2 mapping into clinical workflow it is critical to establish normal reference values.
Goal(s): We defined normal ranges for hepatic T2 values using a 1.5T General Electric scanner.
Approach: Multi-echo fast-spin-echo sequences were acquired in 100 healthy volunteers and T2 values were quantified in the visible hepatic segments.
Results: Segmental and global liver T2 values exhibited a good intra- and inter-observer reproducibility. No significant regional T2 variability was detected. Global T2 values were not associated with aging but were significantly lower in males than in females.
Impact: In healthy subjects liver T2 mapping is feasible and reproducible and T2 values are influenced by gender, suggesting the need for the use of normative values differentiated by gender.
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