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Abstract #4166

Push-button liver DCE MRI: free-breathing, high-resolution 3D DCE with T1 mapping using multitasking joint reconstruction

Qi Liu1, Zihao Chen1,2, Qiufeng Liu3, Hualing Li3, Yang Yang3, Debiao Li2,4, and Jian Xu1
1United Imaging Healthcare, Houston, TX, United States, 2Department of Bioengineering, University of California, Los Angeles (UCLA), Los Angeles, CA, United States, 3Department of Radiology, Tongji Hospital of Tongji Medical College, Wuhan, China, 4Biomedical Imaging Research Institute, Cedars-Sinai Medical Center, Los Angeles, CA, United States

Synopsis

Keywords: Liver, Liver, DCE

Motivation: To address the pain points in clinical abdomen DCE, including sacrifice of spatial resolution for temporal resolution, repeated breath-hold, risk of missing contrast arrival, and the need for separate T1 mapping scan.

Goal(s): To develop an all-in-one, push-button abdomen DCE technique that improves kinetic mapping.

Approach: It was developed using MR multitasking joint reconstruction and tested on volunteer and phantom.

Results: Its feasibility was proven. Its feature includes free-breathing, high spatial and temporal resolution, and embedded T1 and B1 mapping for kinetic modeling correction.

Impact: Abdomen DCE with the proposed MR multitasking joint reconstruction approach can make clinical liver DCE more accessible, more accurate and hassle-free, allowing further researches on DCE in liver disease diagnosis.

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