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Abstract #4168

Non-contrast Time-resolved 4D MR Angiography Reconstruction using Compressed Sensing with Sparsity Regularization and Subspace Modeling

Linzheng Hong1, Dong Wang2, Jun Xie2, and Haikun Qi1
1School of Biomedical Engineering, ShanghaiTech University, Shanghai, China, Shanghai, China, 2United Imaging Healthcare, Shanghai, China, Shanghai, China

Synopsis

Keywords: Sparse & Low-Rank Models, Image Reconstruction

Motivation: ASL-based non-contrast enhanced (non-CE) time-resolved 4D MRA is a promising approach in the diagnosis of cerebrovascular disease, however, it suffers from low SNR and insufficient spatial and temporal resolution.

Goal(s): Our goal was to enhance the quality of 4D non-CE MRA and diminish artifacts.

Approach: This study proposed a novel reconstruct method combining the angiography sparsity and subspace modeling on data acquired by golden-angle stack-of-stars radial pulse sequence.

Results: The performance of the proposed method was compared with NUFFT, conventional GRASP and the state-of-the-art GRASP-pro reconstructions. The results suggest that the proposed method improves the image quality of the 4D ASL-based non-CE MRA.

Impact: The proposed reconstruction method can produce 4D non-CE MRA with high spatial-temporal resolution.

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Keywords