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Abstract #4178

Zero-FRESCO: Zero-Shot Fast REconstruction for Multi-Shot Sensitivity EnCOded Diffusion MRI

Ismail Arda Vurankaya1, Jaejin Cho2,3, Yohan Jun2,3, and Berkin Bilgic2,3
1Electrical and Electronics Engineering, Bogazici University, Istanbul, Turkey, 2Athinoula A. Martinos Center for Biomedical Imaging, Massachusetts General Hospital, Charlestown, MA, United States, 3Department of Radiology, Harvard Medical School, Boston, MA, United States

Synopsis

Keywords: Image Reconstruction, Image Reconstruction

Motivation: Self-supervised neural network reconstruction improves multi-shot diffusion MRI (dMRI), yet suffers from prohibitively long computation times.

Goal(s): To develop a zero-shot self-supervised learning method for fast multi-shot dMRI reconstruction.

Approach: We propose a physics-guided neural network that operates in both k- and image-spaces to combine information from different EPI shots. We show that reconstruction quality can be improved with a novel sampling mask strategy, and that faster training is possible with a new training strategy. Finally, we extend our results to SMS acquisitions.

Results: Our results show that the proposed method provides improved and fast reconstructions compared to 2-shot LORAKS and 2-shot ZS-SSL.

Impact: The proposed physics-guided self-supervised learning method provides fast and high-quality reconstruction of multi-shot diffusion MRI volumes, while also eliminating the need for external training datasets.

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Keywords