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Abstract #4241

tDCS strengthens brain network stability and efficiency after 24-hour total sleep deprivation: a resting state fMRI study

Jiyuan Li1 and Yunlong Yue1
1Department of MRI, Beijing Shijitan Hospital, Capital Medical University, Beijing, China

Synopsis

Keywords: Task/Intervention Based fMRI, fMRI (resting state)

Motivation: tDCS clinical expansion application

Goal(s): Investigating the value of tDCS in brain networks returning to the "rebalance state" of total sleep deprivation

Approach: A repeated-measures pre-to-post design was used. 16 healthy subjects received two 24-hour SD intervals and were randomly given True/Sham tDCS after SD. fMRI data and 2-back task testing were collected after true and sham tDCS, respectively. Observing the changes in topological properties of the whole-brain network.

Results: The topological properties of the whole brain network tend to be in a "rebalanced state" after tDCS.

Impact: Based on the results of this research, tDCS may be more widely applied to intervene in brain functional network disorders.

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Keywords