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Abstract #4268

RESOLVE for simultaneous mapping high-frequency conductivity and micro-structure parameters in conductivity tensor imaging (CTI)

Tong Sun1, Songxiong Wu2, Nashan Wu2, Qingjun Sun2, Haodong Qin3, Guangyao Wu2, Xin Chen1, and Chunqi Chang1
1Shenzhen University, Shenzhen, China, 2Radiology Department, Shenzhen University General Hospital and Shenzhen University Clinical Medical, Shenzhen University General Hospital, Shenzhen, China, 3Siemens Healthineers, Guangzhou, China, Siemens Healthineers, Shenzhen, China

Synopsis

Keywords: Quantitative Imaging, Electromagnetic Tissue Properties, Biomarkers

Motivation: Conventional two sequences acquisition in conductivity tensor imaging (CTI) can cause geometric mismatch between two acquisition data which may influence subsequent reconstruction.

Goal(s): We aim to simultaneously reconstruct the high-frequency conductivity and to fit microstructure parameters with data from single sequence.

Approach: We propose a novel data acquisition strategy which reconstructs the high-frequency conductivity from the phase of non-diffusion weighted data of RESOLVE.

Results: The reconstructed high-frequency conductivity and fitted microstructure parameters has matched geometric images, and the low-frequency conductivity can be successfully reconstructed.

Impact: We show the conventional two sequence acquisition is reduced to the single sequence acquisition which avoids the geometric mismatch and obtains higher precision of low-frequency conductivity.

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Keywords