Abstract #4280

Automatically Quantitative Intra-tumoral susceptibility Signal and R2 star in discriminating subtype of ovarian cancer

Qingling Song¹, Ailian Liu², Ye Li², Li Hao³, Yuting Shi², Qingwei Song², Hongkai Wang^4,5, and Mingrui Zhuang⁴

¹Radiology, The First Affiliated Hospital, Dalian Medical University, Dalian, China, ²Radiology, The First Affiliated Hospital of Dalian Medical University, Dalian, China, ³Radiology, Dalian Municipal Central Hospital, Dalian, Liaoning, China, Dalian, China, ⁴School of Biomedical Engineering, Faculty of Medicine, Dalian University of Technology, Dalian, China, ⁵Liaoning Key Laboratory of Integrated Circuit and Biomedical Electronic System, Dalian, China

Synopsis

Keywords: Pelvis, Blood vessels

Motivation: It is important to quantitatively analyze the subtype of epithelial ovarian cancer using oxygen content, neovascularization, intra-tumoral hemorrhage.

Goal(s): To investigate the R2* value of ESWAN and quantitative ITSS obtained automatically in discriminating subtype of epithelial ovarian cancer.

Approach: R2* value of ESWAN sequence and ITSS ratio of ovarian cancer lesion were measured, and the value of R2* and ITSS in discriminating subtype of EOC was analyzed.

Results: The area ITSS ratio and volume ITSS ratio of type II ovarian cancer were significantly higher than those of type I EOC. There was no significant difference between type I and type II EOC.

Impact: The area ITSS ratio and volume ITSS ratio have certain value in discriminating type I from type II EOC. The value of R2* value in the differentiation of subtype of epithelial ovarian cancer need to be further explored.

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