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Abstract #4300

Characterising placental contractions

Penny Gowland1, Amy Turnbull1, George Hutchinson1, Louise Dewick2, Ruizhe Li3, Chris Bradley1,4, Xin Chen3, Grazziela Figueredo3, Simon Stockwell5, Divya Ramesh1, Neele Dellschaft1, Kate Walker2, and Nia Jones2
1Sir Peter Mansfield Imaging Centre, School of Physics and Astronomy, University of Nottingham, Nottingham, United Kingdom, 2School of Medicine, University of Nottingham, Nottingham, United Kingdom, 3School of Computer Science, University of Nottingham, Nottingham, United Kingdom, 4National Institute for Health Research, Biomedical Research Centre, Hospital NHS Trust and University of Nottingham, Nottingham, United Kingdom, 5Faculty of Engineering, University of Nottingham, Nottingham, United Kingdom

Synopsis

Keywords: Placenta, Placenta

Motivation: We have previously observed placental contractions and now want to charcterise them further.

Goal(s): To characterise placental contractions (frequency, amplitude and length) in normal pregnancy.

Approach: Dynamic respiratory gated multislice EPI scans acquired for 30 minutes across the pregnant uterus, analyzed by automatic segmentation.

Results: Placental contractions lasting several minutes and sometimes causing very large changes in placental volume, were found in every woman studied.

Impact: Further work will investigate the function of contractions and whether they are altered in compromised pregnancies.

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