Abstract #4313

Classification of MRI-only suspicious breast lesions: Development and validation of a nomogram combining MRI features and ADC-based histogram

Xue Li¹, Min Chen², Lei Jiang², Chunmei Li², and Dandan Zheng³

¹Radiology, Department of Radiology, Beijing Hospital, National Center of Gerontology, Institute of Geriatric Medicine, Chinese Academy of Medical Sciences, Beijing, China, ²Department of Radiology, Beijing Hospital, National Center of Gerontology, Institute of Geriatric Medicine, Chinese Academy of Medical Sciences, Beijing, China, ³Clinical & Technical Support, Philips Healthcare, Beijing, China

Synopsis

Keywords: Breast, Breast, Magnetic resonance imaging; Nomogram; Diffusion-weighted imaging; Histogram analysis

Motivation: MRI-only lesions tend to be small in size and often have limited specific morphologic features on MRI, posing a significant diagnostic challenge for clinicians.

Goal(s): A simple, objective, and noninvasive approach is required to improve the diagnostic accuracy of MRI-only lesions.

Approach: We aimed to develop and validate a nomogram combining clinicoradiologic features and ADC-based histogram parameters for MRI-only suspicious lesions.

Results: Our results showed that ADC entropy in histogram parameters and kinetic pattern in clinicoradiologic parameters were identified as the most valuable predictors for differentiating MRI-only lesions, and a nomogram combining them exhibited better diagnostic performance than the two variables alone.

Impact: A nomogram combining ADC entropy and kinetic pattern, as a simple, objective, and noninvasive tool, displays satisfactory diagnostic performance for MRI-only suspicious lesions and may be utilised to avoid unnecessary biopsy.

How to access this content:

For one year after publication, abstracts and videos are only open to registrants of this annual meeting. Registrants should use their existing login information. Non-registrant access can be purchased via the ISMRM E-Library.

After one year, current ISMRM & ISMRT members get free access to both the abstracts and videos. Non-members and non-registrants must purchase access via the ISMRM E-Library.

After two years, the meeting proceedings (abstracts) are opened to the public and require no login information. Videos remain behind password for access by members, registrants and E-Library customers.

Click here for more information on becoming a member.