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Abstract #4318

Characteristics of renal amide proton transfer imaging in a healthy population

Sheng Zhang1, Xia Wang1, Xiaofan Liu1, Chanjuan Yu1, Gang Tian1, Xiuzheng Yue2, and Yuedong Han1
1Xi'an GaoXin Hospital, Xi'an, China, 2Philips Healthcare, Xi'an, China

Synopsis

Keywords: Kidney, Kidney, normal right kidney; amide proton transfer; characteristic

Motivation: The changes in renal protein levels are closely related to physiological and pathological functions. Amide proton transfer weighted (APTw) imaging has the function of non-invasive and targeted detection of tissue-free proteins or peptides and is of great significance in the preliminary study of acute and chronic kidney diseases.

Goal(s): The study of APT imaging in normal kidneys still needs to be completed

Approach: The APT images study of 49 volunteers in this study.

Results: The APT values of the renal cortex and medulla were consistent, and the medulla was significantly higher than the cortex.

Impact: APT imaging is initially applied to the urinary system, such as chronic kidney disease, kidney cancer, etc. In this study, the application value of APTw imaging in renal dermal medulla was investigated

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