Keywords: Image Reconstruction, CEST & MT
Motivation: To make qCEST clinically feasible by reducing the imaging time
Goal(s): Multitasking steady-state (SS) approach was used to get 3D volume acquisition that reduced the imaging time per slice by a factor of 22 as compared to conventional qCEST.
Approach: 6 Yucatan minipigs were scanned at four time points post interverbal disk injury. The injury was done at the lower three lumbar discs. Conventional 2D qCEST and 3D Multitasking steady state CEST were performed.
Results: Scan time for conventional qCEST is 24 minutes/slice while the imaging time for Multitasking SS qCEST is 36 minutes for 32 slices, representing a factor of 22 improvement.
Impact: This study represents the initial step in validating an accelerated qCEST using Multitasking. The development of MRI-based pain assessment biomarkers in this model is crucial for advancing our understanding and treatment of lower back pain.
How to access this content:
For one year after publication, abstracts and videos are only open to registrants of this annual meeting. Registrants should use their existing login information. Non-registrant access can be purchased via the ISMRM E-Library.
After one year, current ISMRM & ISMRT members get free access to both the abstracts and videos. Non-members and non-registrants must purchase access via the ISMRM E-Library.
After two years, the meeting proceedings (abstracts) are opened to the public and require no login information. Videos remain behind password for access by members, registrants and E-Library customers.
Keywords