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Abstract #4547

A Novel Renal 3D Saturation Recovery T1 Mapping readout by GRASE (3D-SR-GRASE)

Wenyan Zhang1,2,3, Quan Tao2,3,4, Zelong Chen5, Kan Deng6, Zhigang Wu7, Yizhe Zhang1,2,3, Qianqian Zhang1,2,3, Yikai Xu5, and Yanqiu Feng1,2,3,4
1School of Biomedical Engineering, Southern Medical University, Guangzhou, China, 2Guangdong Provincial Key Laboratory of Medical Image Processing, Southern Medical University, Guangzhou, China, 3Guangdong Provincial Engineering Laboratory for Medical Imaging and Diagnostic Technology, Southern Medical University, Guangzhou, China, 4Department of Rehabilitation Medicine, Zhujiang Hospital, Southern Medical University, Guangzhou, China, 5Medical Imaging Center, Nanfang Hospital, Southern Medical University, Guangzhou, China, 6Philips Healthcare, Guangzhou, China, 7Philips Healthcare, Shenzhen, China

Synopsis

Keywords: Quantitative Imaging, Quantitative Imaging

Motivation: Renal T1 mapping has been explored as a tool to visualize localized and diffuse renal diseases. 2D-MOLLI imaging have limited coverage, and 3D imaging are currently focused on cardiac imaging and with long acquisition time.

Goal(s): In this study, we aimed to propose a fast 3D T1 mapping sequence for kidney.

Approach: A saturate-recovery(SR) pulse, followed by 3D-GRASE readout, is used for T1 mapping. We also verified its effectiveness in T1 mapping for phantom and normal volunteers.

Results: The proposed sequence allows for 3D renal T1 imaging within two minutes and measured T1 value in phantom and volunteers were consensus with 2D-MOLLI.

Impact: This SR-GRASE sequence may provide a 3D fast clinical imaging technique for kidney.

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Abstract

Keywords