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Abstract #4549

Score-based Diffusion Models with Self-supervised Learning for Accelerated 3D Multi-contrast Cardiac MR Imaging

Yuanyuan Liu1, Zhuo-Xu Cui1, Congcong Liu1, Qingyong Zhu1, Jing Cheng1, Dong Liang1, and Yanjie Zhu1
1Shenzhen Institute of Advanced Technology, Chinese Academy of Sciences, Shenzhen, China

Synopsis

Keywords: Quantitative Imaging, Machine Learning/Artificial Intelligence, 3D cardiac magnetic resonance imaging, self-supervised, diffusion models, multi-contrast

Motivation: Long scan time significantly hinders the widespread applications of three-dimensional multi-contrast cardiac magnetic resonance (3D-MC-CMR) imaging.

Goal(s): This study aims to accelerate 3D-MC-CMR acquisition by a novel method based on score-based diffusion models with self-supervised learning.

Approach: We first establish a mapping between the undersampled k-space measurements and the MR images, utilizing a self-supervised Bayesian reconstruction network. Secondly, we develop a joint score-based diffusion model on 3D-MC-CMR images to capture their inherent distribution. The 3D-MC-CMR images are finally reconstructed using the conditioned Langenvin Markov chain Monte Carlo (MCMC) sampling.

Results: This approach enables accurate reconstruction with high acceleration rates up to 14.

Impact: The proposed method is trained in a self-supervised manner and therefore particularly suited for 3D CMR imaging that lacks fully sampled data.

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