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Abstract #4565

Single-shot and multi-shot cardiac diffusion MRI in vivo using high-amplitude gradient of 200mT/m

Kévin Moulin1,2,3, Thomas Troalen4, Peter Speier5, Pierre Croisille2,3, and Magalie Viallon2,3
1Boston Children's Hospital, Boston, MA, United States, 2CREATIS UMR 5220, U1206, Lyon, France, 3Radiology department, Centre Hospitalier Universitaire de Saint-Étienne, Saint-Etienne, France, 4Siemens Healthcare SAS, Courbevoie, France, 5Siemens Healthcare GmbH, Erlangen, Germany

Synopsis

Keywords: Data Acquisition, Diffusion Tensor Imaging, Cardiac Diffusion Tensor Imaging

Motivation: High gradient hardware has the potential to reduce TE and improve SNR for Cardiac diffusion tensor imaging (cDTI) for both single-shot (SS-EPI) and multi-shot EPI (MS-EPI) approaches. However, gradient amplitude and slew rate can be limited due to Peripheral and Cardiac Nerve stimulation (PNS/CNS).

Goal(s): To compare Gmax=200mT/m and Gmax=80mT/m systems for cDTI.

Approach: Healthy volunteers (n=3) were imaged on both systems using SS-EPI and MS-EPI. PNS/CNS and diffusion parametric mapping were compared.

Results: Equivalent diffusion parameters were found for all acquisitions and systems. At Gmax=200mT/m, MS-EPI used the hardware system efficiently due to reduced PNS but remained limited by CNS.

Impact: In this work, we studied hardware limitations due to PNS/CNS for two high-gradient systems for SS-EPI and MS-EPI. MS-EPI reduces image distortions due to B0 inhomogeneities, improves SNR compared to SS-EPI, and used the most efficiently the hardware system.

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Keywords