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Abstract #4606

The Application of High Temporal Resolution Semi-quantitative Dynamic Contrast Enhanced MRI in Predicting Ki-67 Expression in Breast Cancer

Wen Feng1, Junqiang Lei1, Yuhui Xiong2, Yicong Niu3, Zhifan Li1, Qinqin Ma1, and Zihan Wang4
1Radiology, The First Hospital of Lanzhou University, Lanzhou, China, 2GE HealthCare MR Research, Beijing, China, 3Breast Disease, The First Hospital of Lanzhou University, Lanzhou, China, 4Pathology, The First Hospital of Lanzhou University, Lanzhou, China

Synopsis

Keywords: Breast, Breast, MRI; DISCO; DCE; Ki-67

Motivation: It was hoped that a method can come under observation to capture the semi-quantitative hemodynamic characteristics of tumor enhancement, so as to provide richer and more accurate information for the early clinical diagnosis of breast cancer.

Goal(s): To investigate the application value of semi-quantitative parameters of three enhanced sequences of MRI techniques in predicting Ki-67 expression in breast cancer.

Approach: The semi-quantitative parameters of the enhanced images of the three groups were calculated respectively. The predictive parameters of Ki-67 expression in breast cancer were obtained by statistical analysis.

Results: ROI1+54-per-brevity of enhancement was valuable for predicting the expression of Ki-67 in breast cancer(P=0.032).

Impact: The DISCO-MRI with fast scanning speed and high time resolution needs to be further studied whether it can replace the traditional DCE-MRI scanning in the future, and it also needs to find a suitable post-processing mode.

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Keywords