Keywords: Breast, Breast
Motivation: Accurately evaluating the ALN status is pivotal for both prognosis and treatment planning, especially in the context of decreasing axillary surgery.
Goal(s): This retrospective study aimed to develop a radiomics nomogram for preoperative prediction of ALN status in clinical T1-2 stage invasive breast cancer patients.
Approach: Radiomics features were extracted from ultrafast DCE-MRI and DWI, and clinical characteristics were incorporated to construct a radiomics nomogram.
Results: A radiomics signature achieved AUCs of 0.831 and 0.821 in training and validation cohorts, respectively. The radiomics nomogram, incorporating this signature, multifocality, and MRI-reported ALN status, showed superior performance with AUCs of 0.890 and 0.905.
Impact: The proposed nomogram could be valuable for noninvasively assessing ALN status, aiding prognosis and treatment planning while reducing the need for axillary surgery in breast cancer patients.
How to access this content:
For one year after publication, abstracts and videos are only open to registrants of this annual meeting. Registrants should use their existing login information. Non-registrant access can be purchased via the ISMRM E-Library.
After one year, current ISMRM & ISMRT members get free access to both the abstracts and videos. Non-members and non-registrants must purchase access via the ISMRM E-Library.
After two years, the meeting proceedings (abstracts) are opened to the public and require no login information. Videos remain behind password for access by members, registrants and E-Library customers.
Keywords