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Abstract #4638

Diffusion and Perfusion Measurements of Uterine Corpus Fluctuate During Menstrual Cycle: an IVIM based study

Lei Deng1, Wanxu Ren2, Ali Shang1, Xiaocheng Wei3, Xiaohui Li1, and Quanxin Yang1
1The Second Affiliated Hospital of Xi'an Jiaotong University, Xi'an, China, 2Xian Yang Central Hospital, Xian Yang, China, 3GE HealthCare MR Research, Beijing, China

Synopsis

Keywords: Uterus, Perfusion

Motivation: Correct identification of the typical appearance of the distinct uterine corpus layers during the menstrual cycle is crucial for evaluating uterine lesions.

Goal(s): To investigate the diffusion and perfusion of uterine corpus fluctuate during menstrual cycle.

Approach: Thirty-one volunteers underwent standard pelvic IVIM-DWI in menstrual period, mid-proliferative period and mid-secretory period. The differences of D, D*, f and f ×D* among three-layer structure or different menstrual period were compared.

Results: It was found that an exacerbation of diffusion restriction, occurring from the menstrual period to the mid-secretory period, and perfusion driven by IVIM of uterine corpus was generally decreased, especially in endometrium.

Impact: Considering the menstrual status is necessary on assessment of uterine lesions. It is recommended to study uterine lesions within the same menstrual cycle.

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