Keywords: Motion Correction, Liver, Perfusion
Motivation: The requirements for multiple breath-holds would cause motion artifacts, which may impair the accurate evaluation of lesion properties in dynamic perfusion scans.
Goal(s): To evaluate the clinical feasibility of free-breathing dynamic liver MR perfusion(FBP) compared with breath-holding dynamic perfusion(BHP) method.
Approach: A case-control study of 58 oncology patients were collected. The image quality, intervolume motion effect and diagnostic confidence were compared between the two groups.
Results: Four-dimensional free-breathing dynamic liver MR perfusion (4D-FBP) could provide comparable image quality but significantly fewer motions than routine method, making 4D-FBP an attractive alternative to existing breath-holding techniques in clinical dynamic liver MR scans.
Impact: Free-breathing dynamic liver MR perfusion provides significantly improved intervolume motion and comparable image quality in comparison to the routine breath-holding method, which may promote the clinical translation of liver quantitative perfusion.
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