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Abstract #4661

MR Sequence Design in the Low Stochastic Regime - Development of a Low-SAR “T2-Weighted” Scan

Mark Symms1, James Grist2, Jeff McGovern3, and Damian Tyler4
1GE Healthcare, London, United Kingdom, 2Department of Radiology, Oxford University Hospitals, Oxford Centre for Clinical Magnetic Resonance Research, Oxford, United Kingdom, 3GE Healthcare, Waukesha, WI, United States, 4Department of Physiology, Anatomy, and genetics, University of Oxford, Oxford Centre for Clinical Magnetic Resonance Research, Oxford, United Kingdom

Synopsis

Keywords: Acquisition Methods, High-Field MRI

Motivation: The introduction of Machine Learning-based Image Reconstruction ("Deep Learning") offers a fresh opportunity to explore MR parameter space without the restrictive requirement to maximise MR signal.

Goal(s): Demonstrate an application of the Low Stochastic Regime approach using low flip angle refocusing with good SNR and strong tissue contrast.

Approach: Fast Spin Echo (FSE) images were acquired using reduced flip angle refocusing and extended echo train lengths, in combination with Deep Learning-Reconstruction (“DL-Recon”).

Results: Using DL-Recon to effectively weaken the conventional constraint of maximising MR signal, the redesigned sequence produced images with lower RF power deposition but similar contrast to the product CPMG sequence.

Impact: Clinical applications where T2-weighted imaging is SAR-limited.

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