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Abstract #4742

Repeatability and Reproducibility of Pancreatic Proton Density Fat Fraction Measurements Using Manually Drawn Regions of Interest

Edgar A Castellanos1, Kelly Du1, Diana Alba2, Peter Hunt2, Suneil Koliwad2, and Susan Noworolski1
1Departments of 1Radiology and Biomedical Imaging, UCSF, SF, CA, United States, 2Medicine, UCSF, SF, CA, United States

Synopsis

Keywords: Pancreas, Pancreas, Reproducibility, Repeatibility

Motivation: Determination of repeatability and reproducibility is vital to interpreting and determining measurable change of intra organ fat, specifically in small organs like the pancreas.

Goal(s): The goal of this study is to determine if intra-user repeatability and inter-user reproducibility coefficients of manually drawn ROIs on pancreatic fat.

Approach: The approach of this study was to compare manually drawn ROIs within the pancreas between two users and within a single user.

Results: Results indicate that repeatability and inter-user reproducibility of manually drawn ROIs to determine the MRI measured pancreatic fat fraction were consistent within and across users.

Impact: The repeatability and inter-user reproducibility of manually drawn ROIs to determine the MRI measured pancreatic fat fraction yielded consistent measures both within and across users.

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