Keywords: Elastography, Elastography, MRE, Liver, Stiffness, Repeatability, Reproducibility
Motivation: We want contribute to establish MR Elastography as a reliable imaging technique for liver characterization.
Goal(s): To validate the repeatability and reproducibility of a novel, gravitational hepatic MRE system using a generalized multi-shot GRE-MRE sequence.
Approach: 57 health volunteers underwent 2D and 3D hepatic MRE scans on a 3T Siemens scanner. The repeatability was evaluated through repeated volunteer scans without repositioning, while reproducibility was performed by re-positioning the volunteer after each acquisition.
Results: The repeatability and reproducibility coefficients of 2D-MRE were 0.11, 0.20 and for 3D-MRE, 0.21, 0.24, respectively. Repeatability and reproducibility for the 2D-MRE to 3D-MRE cases were 0.44 and 0.45, respectively.
Impact: We evaluated a new MRE system provides sufficient mechanical vibration which results in high repeatability and reproducibility. This, in combination with the fast GRE-MRE sequence providing sufficient SNR and PNR, serves as a valuable solution.
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