Keywords: Elastography, Contrast Mechanisms, MRE, OC Pulse,Stiffness estimation
Motivation: Preclinical Magnetic Resonance Elastography (MRE) in small animal models offers valuable insights but often requires invasive methods. This study aims to develop non-invasive MRE for small animal liver examinations.
Goal(s): The specific goal is to compare conventional MEG-based MRE with OC-RARE MRE in terms of signal quality and motion encoding.
Approach: A non-invasive MRE setup was created for in vivo mouse liver studies. Both MEG and OC-RARE MRE were tested on four healthy mice.
Results: OC-RARE MRE showed superior Signal-to-Noise Ratios and improved wave visualization. Notable standard deviations highlight challenges. Nevertheless, OC-RARE MRE holds promise for small animal MRE research advancement.
Impact: hese results underscore a novel wave motion encoding strategy, offering substantial benefits for short T2 tissue studies, potentially reducing high technical error rates and fostering MRE's broader clinical application.
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