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Abstract #4830

Comparison of Stiffness Measurement Variability in MRE Phantoms using Different Passive Drivers

Raphael do Vale Souza1, Jeff Kammerman2, David Rutkowski2, Jitka Starekova1, Phillip J. Rossman3, Kay Pepin4, Diego Hernando5, Jean H. Brittain2, and Scott B. Reeder1
1Department of Radiology, University of Wisconsin-Madison, Madison, WI, United States, 2Calimetrix, Madison, WI, United States, 3Mayo Clinic, Rochester, MN, United States, 4Resoundant, Rochester, MN, United States, 5University of Wisconsin-Madison, Madison, WI, United States

Synopsis

Keywords: Phantoms, Phantoms, Elastography, Stiffness

Motivation: Quantitative quality assurance (QA) methods for magnetic resonance elastography (MRE) are needed for clinical care but are currently unavailable.









Goal(s): Evaluate stiffness measurement variability from two phantoms of different stiffness using four types of passive drivers: two commercial drivers, a custom stand-style driver, and a novel driver integrated into the phantom housing.



Approach: Stiffness measurements were quantified in ten acquisitions in two phantoms of differing stiffness by four passive drivers. Measurement variability was compared by standard deviations and Whisker-and-Box plots.



Results: The integrated driver achieved the best performance with the highest repeatability, ie: lowest variability, compared to the other drivers.



Impact: An MRE phantom equipped with an integrated passive driver could improve repeatability in MRE quality assurance, potentially enhancing the reliability of QA processes in both clinical trials and patient care.



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Keywords