Keywords: Phantoms, Phantoms, ASL, perfusion
Motivation: During longitudinal studies it is important to ensure quality assurance of MRI data. Here we use a commercially available perfusion phantom for QA of ASL in a 40-patient placebo-control study.
Goal(s): The goal of this study was to assess the utility of a perfusion phantom for QA of ASL MRI in a clinical trial setting.
Approach: Inversion recovery T1 measurements and pseudo-continuous ASL at 3 different phantom flow rates were scanned periodically on a 3T MRI system over a 36 month period.
Results: Once data due to errant phantom behaviour was discounted, the QA metric of labelling efficiency was in a reasonable range.
Impact: By acquiring independent T1 measures of the phantom’s perfusate, then computing ASL perfusion maps and comparing against the phantom’s pump flow rate, a useful QA metric can be established that can provide confidence in acquired subject ASL data.
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