Keywords: Myocardium, Diffusion/other diffusion imaging techniques, acute myocardial infarction, reperfusion injury
Motivation: Cardiac diffusion-weighted(DW)imaging has proven to be an effective approach to explore ischemia reperfusion myocardium damage and inflammation induced by treatment after reperfusion.
Goal(s): The objective of this study was to investigate whether contrast agent (CA) administration significantly affects DWI in the evaluation of reperfused acute myocardial infarction.
Approach: The apparent diffusion coefficient (ADC) values,signal intensity(SI) and contrast-to-noise ratio(CNR) pre- and post-contrast were measured in the intramyocardial hemorrhage (IMH),edema area and remote regions, respectively.
Results: The ADC values in IMH and edema area were not significantly changed between pre- and post-contrast (P>0.05), while the SI of remote myocardium was inhibited and CNRs were reduced.
Impact: To better assess ischemia reperfusion myocardium damage, DWI is recommended to perform as much as possible before the gadolinium-based contrast agent administration.
How to access this content:
For one year after publication, abstracts and videos are only open to registrants of this annual meeting. Registrants should use their existing login information. Non-registrant access can be purchased via the ISMRM E-Library.
After one year, current ISMRM & ISMRT members get free access to both the abstracts and videos. Non-members and non-registrants must purchase access via the ISMRM E-Library.
After two years, the meeting proceedings (abstracts) are opened to the public and require no login information. Videos remain behind password for access by members, registrants and E-Library customers.
Keywords