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Abstract #4953

A comparison of different sources of soy lecithin for the production of MRI phantoms with systematic analysis of effects on T1, T2, and diffusion

Victor Fritz1,2,3, Petros Martirosian1, Jürgen Machann1,2,3, and Fritz Schick1
1Department of Diagnostic and Interventional Radiology, University of Tuebingen, Section on Experimental Radiology, Tübingen, Germany, 2Institute for Diabetes Research and Metabolic Diseases of the Helmholtz Centre Munich at the University of Tuebingen, Tübingen, Germany, 3German Center for Diabetes Research (DZD), Neuherberg, Germany

Synopsis

Keywords: Phantoms, Phantoms

Motivation: While soy lecithin has been shown to be a beneficial substance for the production of diffusion phantoms, there is no research to date on whether this applies generally or only to specific product sources of soy lecithin.

Goal(s): To investigate the variability of the MR-related properties of three different types of soy lecithin (SL-1,SL-2,SL-3).

Approach: Aqueous soy lecithin solutions of different concentrations were prepared for all three soy lecithin sources and examined using DWI and Relaxometry.

Results: It was found that the MR-related properties of aqueous soy lecithin solutions are dependent on the type of soy lecithin used.

Impact: This work shows that MR properties of soy lecithin strongly depend on the product source. Related effects must be considered for the production of phantoms with tissue-like relaxation and diffusion properties.

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Keywords