Abstract #4962

Fast and accurate 31P B1-mapping at high magnetic fields with short TRs.

Mark Stephan Widmaier^1,2, Antonia Kaiser¹, Salome Baup¹, Ying Xiao^3,4, Yun Jiang⁵, Zhiwei Huang^2,3, Daniel Wenz¹, and Lijing Xin¹

¹Animal imaging and technology core, CIBM Center for Biomedical Imaging, École Polytechnique Fédérale de Lausanne (EPFL), Lausanne, Switzerland, ²Laboratory for Functional and Metabolic Imaging, École Polytechnique Fédérale de Lausanne (EPFL), Lausanne, Switzerland, ³Animal imaging and technology core, CIBM Center for Biomedical Imaging, École polytechnique fédérale de Lausanne (EPFL), Lausanne, Switzerland, ⁴Laboratory for Functional and Metabolic Imaging, Ecole Polytechnique Fédérale de Lausanne (EPFL), Lausanne, Switzerland, ⁵Department of Radiology, Case Western Reserve University, Cleveland, Cleveland, OH, United States

Synopsis

Keywords: RF Pulse Design & Fields, RF Pulse Design & Fields, DAM, 31P, B1 mapping, fast B1, MRSI, X-Nuclei

Motivation: Fast and accurate B1 mapping for³¹P MRI is challenging due to the low sensitivity of ³¹P nucleus and its long T1 relaxation times.

Goal(s): This study aims to develop a fast B1 mapping approach for ³¹P at 7T.

Approach: A look-up table approach was adopted to enable B1 mapping at short TR. Fast spiral encoding together with weighted averaging was implemented with a GRE sequence to further accelerate the acquisition.

Results: B1 mapping was validated in phantom and in vivo in human calf muscle and brain within a scan time of 10min.

Impact: The presented fast and accurate B1 mapping correction method is particularly suited for moderate to short repetition times, showing promise for future applications in rapid X-nuclei imaging.

How to access this content:

For one year after publication, abstracts and videos are only open to registrants of this annual meeting. Registrants should use their existing login information. Non-registrant access can be purchased via the ISMRM E-Library.

After one year, current ISMRM & ISMRT members get free access to both the abstracts and videos. Non-members and non-registrants must purchase access via the ISMRM E-Library.

After two years, the meeting proceedings (abstracts) are opened to the public and require no login information. Videos remain behind password for access by members, registrants and E-Library customers.

Click here for more information on becoming a member.