Meeting Banner
Abstract #4968

Functional brain network reconfiguration from rest to movie changes across repeated movie-viewing and associates with free recall performance

Eric Kwun Kei Ng1, Wan Lin Yue1, Xing Qian1, Kian Foong Wong1, Michael W L Chee1, and Juan Helen Zhou1,2,3,4
1Centre for Sleep and Cognition, Yong Loo Lin School of Medicine, National University of Singapore, Singapore, Singapore, 2Centre for Translational MR Research, Yong Loo Lin School of Medicine, National University of Singapore, Singapore, Singapore, 3Integrative Sciences and Engineering Programme, NUS Graduate School, National University of Singapore, Singapore, Singapore, 4Department of Electrical and Computer Engineering, National University of Singapore, Singapore, Singapore

Synopsis

Keywords: Functional Connectivity, fMRI, functional reconfiguration, movie paradigm

Motivation: It remains unclear if brain functional reconfiguration from resting state is cognitively relevant for naturalistic conditions.

Goal(s): To establish changes in brain functional connectivity (FC) similarity between rest and repeated movie watching and their relation with memory in young adults.

Approach: We studied intra- and inter network FC similarity changes across 3 movie-viewing BOLD fMRI sessions, and correlated similarity measures with memory recall scores of one movie.

Results: Movies with higher cognitive load and narrative structure evidenced stronger changes in rest-movie functional reconfiguration across sessions; association with recall scores shifted from sensory networks to associative networks over sessions. Higher similarity was more advantageous.

Impact: Rest-movie functional reconfiguration lent support to the hypothesis that less reconfiguration may reflect higher information processing efficiency by brain functional networks. It further informs memory encoding and retrieval in naturalistic contexts.

How to access this content:

For one year after publication, abstracts and videos are only open to registrants of this annual meeting. Registrants should use their existing login information. Non-registrant access can be purchased via the ISMRM E-Library.

After one year, current ISMRM & ISMRT members get free access to both the abstracts and videos. Non-members and non-registrants must purchase access via the ISMRM E-Library.

After two years, the meeting proceedings (abstracts) are opened to the public and require no login information. Videos remain behind password for access by members, registrants and E-Library customers.

Click here for more information on becoming a member.

Keywords

movie