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Abstract #5025

Improved depiction of habenula with optimized high-resolution STAGE

Bingyang Bian1, Lei Zhang1, E. Mark Haacke2, Lin Hou1, Yueluan Jiang3, and Tao Li4
1radiology department, Bethune First Hospital of Jilin University, Changchun, China, 2Department of Biomedical Engineering, Wayne State University, Detroit, Michigan, MI, United States, 3MR Scientific Marketing, Diagnostic Imaging, Siemens Healthineers Ltd, Beijing, China, 4School of Nursing, Jilin University, Changchun, China

Synopsis

Keywords: Psychiatric Disorders, Psychiatric Disorders, habenula;depressive disorder;STAGE

Motivation: The visualization and identification of humans habenula is particularly challenging in vivo MR imaging due to its subcortical location and small size

Goal(s): To achieve visualization and quantitative analysis of the habenula

Approach: In this work we performed a high-resolution strategically acquired gradient echo protocol at 3T for visualization habenula

Results: We achieved high-definition visualization of habenula, and provided a quantitative multi-parametric characterization of the habenula microstructure in vivo

Impact: We performed an optimized high-resolution sequence, which used to guide future studies optimizing the visualization of habenula. The standardized nature of quantitative MR measurements also provide a baseline from a healthy cohort against which to assess pathological differences.

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Keywords