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Abstract #5094

Cervical Cancer and Paracancerous Tissue ATPw combined with DWI to predict Parametrial infiltration: An Preliminary Study

Lianze Du1, Qinghe Han1, Qinghai Yuan1, and Mengdi Zhang1
1The Second Hospital of Jilin University, Changchun, China

Synopsis

Keywords: fMRI Analysis, fMRI

Motivation: Cervical cancer(CC) is one of the most common gynecological malignancies. Parametrial infiltration (PMI) is considered a decisive factor in the treatment of patients with CC.

Goal(s): This study aimed to investigate the potential of Amide proton transfer-weighted (APTw) in predicting PMI of CC, and to further evaluate whether the APTw parameters of paracancerous tissue can add diagnostic value to diffusion-weighted MRI of CC.

Approach: 81 participants underwent pelvic MRI , including APTw MRI ,and takes measurements.

Results: The results showed that the APTw values ,especially in paracancerous tissues, could be used to efficiently distinguish PMI of cervical cancer.

Impact: APTw values ,especially in paracancerous tissues, could be used to efficiently distinguish PMI of cervical cancer. which can provide additional information to improve the results of diffusion-weighted MRI, thereby assisting further clinical decision-making and improving patient prognosis.

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