Keywords: Microstructure, Diffusion/other diffusion imaging techniques, Tensor-valued encoding, Spiral imaging
Motivation: Improvement of the quantification of the microstructure in the human brain with tensor-valued encoded diffusion MRI.
Goal(s): Obtain whole-brain macro- and microscopic diffusion tensor distribution metrics using spiral k-space trajectories at 7T.
Approach: Two diffusion-weighted sequences realizing the QTI approach were designed with Pulseq. They were compared to each other and to an additionally acquired DTI sequence including a ROI analysis.
Results: Accurate metric maps were obtained which are in accordance with the literature and DTI values.
Impact: Combining a multiband spiral sequence with advanced diffusion weighting enables fast whole-brain mapping of microscopic fractional anisotropy in 11-12 minutes.
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