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Abstract #5107

Improved visualization of high b-value prostate diffusion weighted imaging using LIPO-only multi-shot EPI with 2D navigator (LION-IRIS)

Daichi Murayama1, Masami Yoneyama2, Takayuki Sakai3, Iain Ball4, and Shigehiro Ochi3
1Radiology, Eastern Chiba Medical Center, Chiba, Japan, 2Philips Japan, Tokyo, Japan, 3Eastern Chiba Medical Center, Chiba, Japan, 4Philips Australia & New Zealand, North Ryde, Australia

Synopsis

Keywords: Diffusion Acquisition, Diffusion/other diffusion imaging techniques, fat suppresstion

Motivation: One of the drawbacks of IRIS is its low SNR compared with ss-DWI. High b-value DWI improves the ability of prostate cancer detection by increased cancer conspicuity. However, such high b value images may also suffer from decreased SNR.

Goal(s): We hypothesized that using only slice selection gradient reversal (SSGR, LIPO) technique without fat suppression pre-pulse (LIpo-ONly :LION) could improve the SNR of high b-value IRIS DWI.

Approach: SNR,CR and ADC values were calculated with ROIs placed in internal obturator muscle and prostate region in peripheral zone.

Results: LION IRIS-DWI could provide high quality distortion-free high b-value prostate DWI sufficient SNR.

Impact: The present findings suggest that LION IRISs-DWI sequence demonstrated improved image distortion and blurring compared to ss-DWI, with having sufficient SNR and CR.It may help to further assess the prostate cancer pathology.

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Keywords