Keywords: Diffusion Acquisition, High-Field MRI
Motivation: The SNR benefits of diffusion weighted imaging (DWI) at 7T are unclear. Previous studies comparing across field strengths involved varying scanner hardware and acquisition protocols.
Goal(s): To characterise the spatial SNR differences of brain DWI at 3T and 7T.
Approach: Participants were scanned back-to-back on 3T and 7T scanners with well-matched hardware and acquisition protocols. SNR and DTI metrics were compared between field strengths in white and grey matter regions.
Results: SNR is higher at 7T in WM but comparable or lower in GM. DTI metrics also vary between field strengths, and fitting error is lower at 7T.
Impact: This study indicates that there is tangible SNR benefit to studying white matter using diffusion-weighted imaging at 7T in humans. However, we caution researchers when studying grey matter structures, especially in the pallidum and close to the air-tissue interfaces.
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