Motivation: This abstract focuses on educating on how high-gradient MRI systems can utilize the multi-echo functional MRI (ME-fMRI) techniques.
Goal(s): We explain the blood-oxygen-level-dependent (BOLD) signal technique and how additional echoes can improve the signal fidelity.
Approach: The ME-fMRI, using three or more echoes allow for the pixelwise T2* decay to be modeled, and as BOLD contrast is a function of T2* evolution over time, an experiment sampling the voxel-wise T2* signal decay can be used to separate BOLD from artifact signal constituents.
Results: Gradient systems with ultra-rapid slew rates (> 400 T/m/s) allow ME-fMRI to reduce artefacts from flow, motion, and susceptibility effects.
Impact: MRI systems with ultra-high gradient systems can reduce artefacts from flow, motion, and susceptibility effects in the BOLD contrast technique using an ME-fMRI technique with three or more echoes to improve fidelity of fMRI.
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